Hiltzik: New frontiers in pseudoscientific baloney - Los Angeles Times

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Colossal Biosciences' De-extinction Claim

Colossal Biosciences announced the "de-extinction" of the dire wolf, creating three animals with 15 gene edits from gray wolves. This claim drew both media attention and criticism from the genetics community.

Scientific Controversy

Experts, such as Paul Knoepfler from UC Davis, challenged Colossal's claims, stating that the created animals are not true dire wolves and that the company's hype is harmful to science. Colossal counters that the focus on the name distracts from the scientific achievement of developing new models for ancient DNA extraction.

Marketing vs. Science

Colossal's announcement involved a significant media rollout featuring articles in Time magazine and a segment on Good Morning America. Critics argue that the company prioritized marketing over a nuanced scientific assessment.

  • The website's presentation of the dire wolf project emphasized a successful resurrection, lacking scientific circumspection.
  • Colossal acknowledges the website as marketing, not a peer-reviewed scientific paper.

Ethical and Ecological Concerns

The article discusses ethical and ecological concerns surrounding de-extinction, including:

  • Reviving dangerous pathogens.
  • Resurrected species lacking original habitats.
  • Potential undermining of endangered species protection efforts.

Concerns about de-extinction's impact on conservation efforts were already evident when President Trump's Interior Secretary cited Colossal's work as a reason to potentially overhaul endangered species regulations.

Colossal's Business Model

Colossal has various projects, including the de-extinction of woolly mammoths and dodo birds. The company foresees a potential market for biodiversity credits, similar to carbon credits.

Conclusion

Colossal's work showcases advancements in genetic engineering but its marketing strategy overemphasized the accomplishment. The scientific community questions whether the work truly constitutes de-extinction. Ethical and ecological implications remain a critical consideration.

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